Total IgE

Immunoglobulin E (IgE)

IgE antibodies are produced by only a relatively small proportion of plasma cells at any given time; however, greatly elevated IgE levels are found in some disease states. Measurement of the total circulating IgE level can help distinguish between IgE-mediated and non-IgE-mediated reactions.; it can be also of value in the early detection of allergy in infants and as a means for predicting future atopic manifestations.

Significant elevations may be associated with sensitized individuals, in cases of IgE myeloma, pulmonary aspergillosis, and during the active stage of parasitic infections.

 

 

 


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